Cargando…
The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription
Glis3 is a member of the Krüppel-like family of transcription factors and is highly expressed in islet β cells. Mutations in GLIS3 cause the syndrome of neonatal diabetes and congenital hypothyroidism (NDH). Our aim was to examine the role of Glis3 in β cells, specifically with regard to regulation...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677877/ https://www.ncbi.nlm.nih.gov/pubmed/19264802 http://dx.doi.org/10.1093/nar/gkp122 |