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Island method for estimating the statistical significance of profile-profile alignment scores
BACKGROUND: In the last decade, a significant improvement in detecting remote similarity between protein sequences has been made by utilizing alignment profiles in place of amino-acid strings. Unfortunately, no analytical theory is available for estimating the significance of a gapped alignment of t...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678096/ https://www.ncbi.nlm.nih.gov/pubmed/19379500 http://dx.doi.org/10.1186/1471-2105-10-112 |