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FEM-based oxygen consumption and cell viability models for avascular pancreatic islets
BACKGROUND: The function and viability of cultured, transplanted, or encapsulated pancreatic islets is often limited by hypoxia because these islets have lost their vasculature during the isolation process and have to rely on gradient-driven passive diffusion, which cannot provide adequate oxygen tr...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678100/ https://www.ncbi.nlm.nih.gov/pubmed/19371422 http://dx.doi.org/10.1186/1742-4682-6-5 |