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Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function

BACKGROUND: Transgenic chloroplasts are potential bioreactors for recombinant protein production, especially for achievement of high levels of protein expression and proper folding. Production of therapeutic proteins in leaves provides transgene containment by elimination of reproductive structures....

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Detalles Bibliográficos
Autores principales: Daniell, Henry, Ruiz, Gricel, Denes, Bela, Sandberg, Laurence, Langridge, William
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678116/
https://www.ncbi.nlm.nih.gov/pubmed/19344517
http://dx.doi.org/10.1186/1472-6750-9-33