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Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe?

The metabolic syndrome may have its origins in thriftiness, insulin resistance and one of the most ancient of all signalling systems, redox. Thriftiness results from an evolutionarily-driven propensity to minimise energy expenditure. This has to be balanced with the need to resist the oxidative stre...

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Detalles Bibliográficos
Autores principales: Nunn, Alistair VW, Bell, Jimmy D, Guy, Geoffrey W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678135/
https://www.ncbi.nlm.nih.gov/pubmed/19371409
http://dx.doi.org/10.1186/1743-7075-6-16