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Different skeletal effects of the peroxisome proliferator activated receptor (PPAR)α agonist fenofibrate and the PPARγ agonist pioglitazone

BACKGROUND: All the peroxisome proliferator activated receptors (PPARs) are found to be expressed in bone cells. The PPARγ agonist rosiglitazone has been shown to decrease bone mass in mice and thiazolidinediones (TZDs) have recently been found to increase bone loss and fracture risk in humans treat...

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Detalles Bibliográficos
Autores principales: Syversen, Unni, Stunes, Astrid K, Gustafsson, Björn I, Obrant, Karl J, Nordsletten, Lars, Berge, Rolf, Thommesen, Liv, Reseland, Janne E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678137/
https://www.ncbi.nlm.nih.gov/pubmed/19331671
http://dx.doi.org/10.1186/1472-6823-9-10