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Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development

BACKGROUND: Down syndrome is a chromosomal disorder caused by the presence of three copies of chromosome 21. The mechanisms by which this aneuploidy produces the complex and variable phenotype observed in people with Down syndrome are still under discussion. Recent studies have demonstrated an incre...

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Detalles Bibliográficos
Autores principales: Laffaire, Julien, Rivals, Isabelle, Dauphinot, Luce, Pasteau, Fabien, Wehrle, Rosine, Larrat, Benoit, Vitalis, Tania, Moldrich, Randal X, Rossier, Jean, Sinkus, Ralph, Herault, Yann, Dusart, Isabelle, Potier, Marie-Claude
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678156/
https://www.ncbi.nlm.nih.gov/pubmed/19331679
http://dx.doi.org/10.1186/1471-2164-10-138