Mutations in genes involved in nonsense mediated decay ameliorate the phenotype of sel-12 mutants with amber stop mutations in Caenorhabditis elegans

BACKGROUND: Presenilin proteins are part of a complex of proteins that can cleave many type I transmembrane proteins, including Notch Receptors and the Amyloid Precursor Protein, in the middle of the transmembrane domain. Dominant mutations in the human presenilin genes PS1 and PS2 lead to Familial...

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Detalles Bibliográficos
Autores principales: Gontijo, Alisson M, Aubert, Sylvie, Roelens, Ingele, Lakowski, Bernard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678165/
https://www.ncbi.nlm.nih.gov/pubmed/19302704
http://dx.doi.org/10.1186/1471-2156-10-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678165/
https://www.ncbi.nlm.nih.gov/pubmed/19302704
http://dx.doi.org/10.1186/1471-2156-10-14

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