IL-6 Mediated Degeneration of Forebrain GABAergic Interneurons and Cognitive Impairment in Aged Mice through Activation of Neuronal NADPH Oxidase

BACKGROUND: Multiple studies have shown that plasma levels of the pro-inflammatory cytokine interleukin-6 (IL-6) are elevated in patients with important and prevalent adverse health conditions, including atherosclerosis, diabetes, obesity, obstructive sleep apnea, hypertension, and frailty. Higher p...

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Detalles Bibliográficos
Autores principales: Dugan, Laura L., Ali, Sameh S., Shekhtman, Grigoriy, Roberts, Amanda J., Lucero, Jacinta, Quick, Kevin L., Behrens, M. Margarita
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678193/
https://www.ncbi.nlm.nih.gov/pubmed/19436757
http://dx.doi.org/10.1371/journal.pone.0005518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678193/
https://www.ncbi.nlm.nih.gov/pubmed/19436757
http://dx.doi.org/10.1371/journal.pone.0005518

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