Use of Tissue-Specific MicroRNA to Control Pathology of Wild-Type Adenovirus without Attenuation of Its Ability to Kill Cancer Cells

Replicating viruses have broad applications in biomedicine, notably in cancer virotherapy and in the design of attenuated vaccines; however, uncontrolled virus replication in vulnerable tissues can give pathology and often restricts the use of potent strains. Increased knowledge of tissue-selective...

Descripción completa

Detalles Bibliográficos
Autores principales: Cawood, Ryan, Chen, Hannah H., Carroll, Fionnadh, Bazan-Peregrino, Miriam, van Rooijen, Nico, Seymour, Leonard W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678247/
https://www.ncbi.nlm.nih.gov/pubmed/19461878
http://dx.doi.org/10.1371/journal.ppat.1000440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678247/
https://www.ncbi.nlm.nih.gov/pubmed/19461878
http://dx.doi.org/10.1371/journal.ppat.1000440

Ejemplares similares