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Use of Tissue-Specific MicroRNA to Control Pathology of Wild-Type Adenovirus without Attenuation of Its Ability to Kill Cancer Cells

Replicating viruses have broad applications in biomedicine, notably in cancer virotherapy and in the design of attenuated vaccines; however, uncontrolled virus replication in vulnerable tissues can give pathology and often restricts the use of potent strains. Increased knowledge of tissue-selective...

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Detalles Bibliográficos
Autores principales:	Cawood, Ryan, Chen, Hannah H., Carroll, Fionnadh, Bazan-Peregrino, Miriam, van Rooijen, Nico, Seymour, Leonard W.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678247/ https://www.ncbi.nlm.nih.gov/pubmed/19461878 http://dx.doi.org/10.1371/journal.ppat.1000440

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