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Genome-Wide Massively Parallel Sequencing of Formaldehyde Fixed-Paraffin Embedded (FFPE) Tumor Tissues for Copy-Number- and Mutation-Analysis

BACKGROUND: Cancer re-sequencing programs rely on DNA isolated from fresh snap frozen tissues, the preparation of which is combined with additional preservation efforts. Tissue samples at pathology departments are routinely stored as formalin-fixed and paraffin-embedded (FFPE) samples and their use...

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Detalles Bibliográficos
Autores principales: Schweiger, Michal R., Kerick, Martin, Timmermann, Bernd, Albrecht, Marcus W., Borodina, Tatjana, Parkhomchuk, Dmitri, Zatloukal, Kurt, Lehrach, Hans
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678265/
https://www.ncbi.nlm.nih.gov/pubmed/19440246
http://dx.doi.org/10.1371/journal.pone.0005548