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The rise and fall of a human recombination hot spot

Human meiotic crossovers mainly cluster into narrow hot spots1 that profoundly influence patterns of haplotype diversity2 and which may also impact on genome instability3 and sequence evolution4-6. Hot spots also appear to be ephemeral7-9 but processes of hot-spot activation and their subsequent evo...

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Detalles Bibliográficos
Autores principales: Jeffreys, Alec J., Neumann, Rita
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678279/
https://www.ncbi.nlm.nih.gov/pubmed/19349985
http://dx.doi.org/10.1038/ng.346