Cargando…
The rise and fall of a human recombination hot spot
Human meiotic crossovers mainly cluster into narrow hot spots1 that profoundly influence patterns of haplotype diversity2 and which may also impact on genome instability3 and sequence evolution4-6. Hot spots also appear to be ephemeral7-9 but processes of hot-spot activation and their subsequent evo...
Autores principales: | Jeffreys, Alec J., Neumann, Rita |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678279/ https://www.ncbi.nlm.nih.gov/pubmed/19349985 http://dx.doi.org/10.1038/ng.346 |
Ejemplares similares
-
PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans
por: Berg, Ingrid L., et al.
Publicado: (2010) -
Anatomy of mouse recombination hot spots
por: Wu, Zhen K., et al.
Publicado: (2010) -
HUMHOT: a database of human meiotic recombination hot spots
por: Nishant, K. T., et al.
Publicado: (2006) -
Human Imprinted Chromosomal Regions Are Historical Hot-Spots of Recombination
por: Sandovici, Ionel, et al.
Publicado: (2006) -
Structural basis for human PRDM9 action at recombination hot spots
por: Patel, Anamika, et al.
Publicado: (2016)