A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain

BACKGROUND: Ubiquitination serves multiple cellular functions, including proteasomal degradation and the control of stability, function, and intracellular localization of a wide variety of proteins. NEDD4L is a member of the HECT class of E3 ubiquitin ligases. A defining feature of NEDD4L protein is...

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Detalles Bibliográficos
Autores principales: Garrone, Nicholas F, Blazer-Yost, Bonnie L, Weiss, Robert B, Lalouel, Jean-Marc, Rohrwasser, Andreas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678989/
https://www.ncbi.nlm.nih.gov/pubmed/19364400
http://dx.doi.org/10.1186/1471-2121-10-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678989/
https://www.ncbi.nlm.nih.gov/pubmed/19364400
http://dx.doi.org/10.1186/1471-2121-10-26

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