Cargando…

Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4

BACKGROUND: Neutrophils play an important role in the pathophysiology of RSV, though RSV does not appear to directly activate neutrophils in the lower airways. Therefore locally produced cytokines or other molecules released by virally-infected airway epithelial cells are likely responsible for recr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wheeler, Derek S, Chase, Margaret A, Senft, Albert P, Poynter, Sue E, Wong, Hector R, Page, Kristen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679007/
https://www.ncbi.nlm.nih.gov/pubmed/19405961
http://dx.doi.org/10.1186/1465-9921-10-31