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Acetylation of PAMAM dendrimers for cellular delivery of siRNA
BACKGROUND: The advancement of gene silencing via RNA interference is limited by the lack of effective short interfering RNA (siRNA) delivery vectors. Rational design of polymeric carriers has been complicated by the fact that most chemical modifications affect multiple aspects of the delivery proce...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679008/ https://www.ncbi.nlm.nih.gov/pubmed/19389227 http://dx.doi.org/10.1186/1472-6750-9-38 |