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Small molecule inhibitors of the Yersinia type III secretion system impair the development of Chlamydia after entry into host cells

BACKGROUND: Chlamydiae are obligate intracellular pathogens that possess a type III secretion system to deliver proteins into the host cell during infection. Small molecule inhibitors of type III secretion in Yersinia, termed INPs (Innate Pharmaceuticals AB) were reported to strongly inhibit Chlamyd...

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Detalles Bibliográficos
Autores principales: Muschiol, Sandra, Normark, Staffan, Henriques-Normark, Birgitta, Subtil, Agathe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679026/
https://www.ncbi.nlm.nih.gov/pubmed/19383140
http://dx.doi.org/10.1186/1471-2180-9-75