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In vitro activity of pyronaridine against Plasmodium falciparum and comparative evaluation of anti-malarial drug susceptibility assays

BACKGROUND: Pyronaridine, a Mannich base anti-malarial with high efficacy against drug resistant Plasmodium falciparum, is currently evaluated as a fixed dose combination with artesunate for the treatment of uncomplicated malaria. In this study, the in vitro activity of pyronaridine against clinical...

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Detalles Bibliográficos
Autores principales: Kurth, Florian, Pongratz, Peter, Bélard, Sabine, Mordmüller, Benjamin, Kremsner, Peter G, Ramharter, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679051/
https://www.ncbi.nlm.nih.gov/pubmed/19389221
http://dx.doi.org/10.1186/1475-2875-8-79