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Complexity in the genetic architecture of leukoaraiosis in hypertensive sibships from the GENOA Study

BACKGROUND: Subcortical white matter hyperintensity on magnetic resonance imaging (MRI) of the brain, referred to as leukoaraiosis, is associated with increased risk of stroke and dementia. Hypertension may contribute to leukoaraiosis by accelerating the process of arteriosclerosis involving penetra...

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Detalles Bibliográficos
Autores principales: Smith, Jennifer A, Turner, Stephen T, Sun, Yan V, Fornage, Myriam, Kelly, Reagan J, Mosley, Thomas H, Jack, Clifford R, Kullo, Iftikhar J, Kardia, Sharon LR
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679055/
https://www.ncbi.nlm.nih.gov/pubmed/19351393
http://dx.doi.org/10.1186/1755-8794-2-16