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Lysophosphatidic Acid-Induced Transcriptional Profile Represents Serous Epithelial Ovarian Carcinoma and Worsened Prognosis

BACKGROUND: Lysophosphatidic acid (LPA) governs a number of physiologic and pathophysiological processes. Malignant ascites fluid is rich in LPA, and LPA receptors are aberrantly expressed by ovarian cancer cells, implicating LPA in the initiation and progression of ovarian cancer. However, there is...

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Detalles Bibliográficos
Autores principales: Murph, Mandi M., Liu, Wenbin, Yu, Shuangxing, Lu, Yiling, Hall, Hassan, Hennessy, Bryan T., Lahad, John, Schaner, Marci, Helland, Åslaug, Kristensen, Gunnar, Børresen-Dale, Anne-Lise, Mills, Gordon B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679144/
https://www.ncbi.nlm.nih.gov/pubmed/19440550
http://dx.doi.org/10.1371/journal.pone.0005583