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Human Neural Stem Cells Genetically Modified to Overexpress Akt1 Provide Neuroprotection and Functional Improvement in Mouse Stroke Model

In a previous study, we have shown that human neural stem cells (hNSCs) transplanted in brain of mouse intracerebral hemorrhage (ICH) stroke model selectively migrate to the ICH lesion and induce behavioral recovery. However, low survival rate of grafted hNSCs in the brain precludes long-term therap...

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Detalles Bibliográficos
Autores principales: Lee, Hong J., Kim, Mi K., Kim, Hee J., Kim, Seung U.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679145/
https://www.ncbi.nlm.nih.gov/pubmed/19440551
http://dx.doi.org/10.1371/journal.pone.0005586