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The UBA-UIM Domains of the USP25 Regulate the Enzyme Ubiquitination State and Modulate Substrate Recognition

USP25m is the muscle isoform of the deubiquitinating (DUB) enzyme USP25. Similarly to most DUBs, data on USP25 regulation and substrate recognition is scarce. In silico analysis predicted three ubiquitin binding domains (UBDs) at the N-terminus: one ubiquitin-associated domain (UBA) and two ubiquiti...

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Detalles Bibliográficos
Autores principales: Denuc, Amanda, Bosch-Comas, Anna, Gonzàlez-Duarte, Roser, Marfany, Gemma
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679190/
https://www.ncbi.nlm.nih.gov/pubmed/19440361
http://dx.doi.org/10.1371/journal.pone.0005571