Cargando…

Adaptive Variation Regulates the Expression of the Human SGK1 Gene in Response to Stress

The Serum and Glucocorticoid-regulated Kinase1 (SGK1) gene is a target of the glucocorticoid receptor (GR) and is central to the stress response in many human tissues. Because environmental stress varies across habitats, we hypothesized that natural selection shaped the geographic distribution of ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Luca, Francesca, Kashyap, Sonal, Southard, Catherine, Zou, Min, Witonsky, David, Di Rienzo, Anna, Conzen, Suzanne D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679193/
https://www.ncbi.nlm.nih.gov/pubmed/19461886
http://dx.doi.org/10.1371/journal.pgen.1000489