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Adaptive Variation Regulates the Expression of the Human SGK1 Gene in Response to Stress
The Serum and Glucocorticoid-regulated Kinase1 (SGK1) gene is a target of the glucocorticoid receptor (GR) and is central to the stress response in many human tissues. Because environmental stress varies across habitats, we hypothesized that natural selection shaped the geographic distribution of ge...
Autores principales: | Luca, Francesca, Kashyap, Sonal, Southard, Catherine, Zou, Min, Witonsky, David, Di Rienzo, Anna, Conzen, Suzanne D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679193/ https://www.ncbi.nlm.nih.gov/pubmed/19461886 http://dx.doi.org/10.1371/journal.pgen.1000489 |
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