Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β

It is widely believed that innate immune responses to Borrelia burgdorferi (Bb) are primarily triggered by the spirochete's outer membrane lipoproteins signaling through cell surface TLR1/2. We recently challenged this notion by demonstrating that phagocytosis of live Bb by peripheral blood mon...

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Detalles Bibliográficos
Autores principales: Salazar, Juan C., Duhnam-Ems, Star, La Vake, Carson, Cruz, Adriana R., Moore, Meagan W., Caimano, Melissa J., Velez-Climent, Leonor, Shupe, Jonathan, Krueger, Winfried, Radolf, Justin D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679197/
https://www.ncbi.nlm.nih.gov/pubmed/19461888
http://dx.doi.org/10.1371/journal.ppat.1000444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679197/
https://www.ncbi.nlm.nih.gov/pubmed/19461888
http://dx.doi.org/10.1371/journal.ppat.1000444

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