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Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β
It is widely believed that innate immune responses to Borrelia burgdorferi (Bb) are primarily triggered by the spirochete's outer membrane lipoproteins signaling through cell surface TLR1/2. We recently challenged this notion by demonstrating that phagocytosis of live Bb by peripheral blood mon...
Autores principales: | Salazar, Juan C., Duhnam-Ems, Star, La Vake, Carson, Cruz, Adriana R., Moore, Meagan W., Caimano, Melissa J., Velez-Climent, Leonor, Shupe, Jonathan, Krueger, Winfried, Radolf, Justin D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679197/ https://www.ncbi.nlm.nih.gov/pubmed/19461888 http://dx.doi.org/10.1371/journal.ppat.1000444 |
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