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Prospective Identification of Malaria Parasite Genes under Balancing Selection

BACKGROUND: Endemic human pathogens are subject to strong immune selection, and interrogation of pathogen genome variation for signatures of balancing selection can identify important target antigens. Several major antigen genes in the malaria parasite Plasmodium falciparum have shown such signature...

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Detalles Bibliográficos
Autores principales: Tetteh, Kevin K. A., Stewart, Lindsay B., Ochola, Lynette Isabella, Amambua-Ngwa, Alfred, Thomas, Alan W., Marsh, Kevin, Weedall, Gareth D., Conway, David J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679211/
https://www.ncbi.nlm.nih.gov/pubmed/19440377
http://dx.doi.org/10.1371/journal.pone.0005568