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Prospective Identification of Malaria Parasite Genes under Balancing Selection
BACKGROUND: Endemic human pathogens are subject to strong immune selection, and interrogation of pathogen genome variation for signatures of balancing selection can identify important target antigens. Several major antigen genes in the malaria parasite Plasmodium falciparum have shown such signature...
Autores principales: | Tetteh, Kevin K. A., Stewart, Lindsay B., Ochola, Lynette Isabella, Amambua-Ngwa, Alfred, Thomas, Alan W., Marsh, Kevin, Weedall, Gareth D., Conway, David J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679211/ https://www.ncbi.nlm.nih.gov/pubmed/19440377 http://dx.doi.org/10.1371/journal.pone.0005568 |
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