Inferring novel disease indications for known drugs by semantically linking drug action and disease mechanism relationships

BACKGROUND: Discovering that drug entities already approved for one disease are effective treatments for other distinct diseases can be highly beneficial and cost effective. To do this predictively, our conjecture is that a semantic infrastructure linking mechanistic relationships between pharmacolo...

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Detalles Bibliográficos
Autores principales: Qu, Xiaoyan A, Gudivada, Ranga C, Jegga, Anil G, Neumann, Eric K, Aronow, Bruce J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679404/
https://www.ncbi.nlm.nih.gov/pubmed/19426461
http://dx.doi.org/10.1186/1471-2105-10-S5-S4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679404/
https://www.ncbi.nlm.nih.gov/pubmed/19426461
http://dx.doi.org/10.1186/1471-2105-10-S5-S4

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