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Inferring novel disease indications for known drugs by semantically linking drug action and disease mechanism relationships
BACKGROUND: Discovering that drug entities already approved for one disease are effective treatments for other distinct diseases can be highly beneficial and cost effective. To do this predictively, our conjecture is that a semantic infrastructure linking mechanistic relationships between pharmacolo...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679404/ https://www.ncbi.nlm.nih.gov/pubmed/19426461 http://dx.doi.org/10.1186/1471-2105-10-S5-S4 |