INACTIVATION OF AMPK ALTERS GENE EXPRESSION AND PROMOTES GROWTH OF PROSTATE CANCER CELLS

AMP-activated protein kinase (AMPK) serves as a fuel-sensing enzyme that is activated by binding of AMP and subsequent phophorylation by upstream kinases such as the tumor suppressor LKB1, when cells sense an increase in the ratio of AMP to ATP. Acute activation of AMPK stimulates fatty acid oxidati...

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Detalles Bibliográficos
Autores principales: Zhou, Jing, Huang, Wei, Tao, Rong, Ibaragi, Soichiro, Lan, Fan, Ido, Yasuo, Wu, Xiaoyun, Alekseyev, Yuriy O., Lendburg, Marc E., Hu, Guo-fu, Luo, Zhijun
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679420/
https://www.ncbi.nlm.nih.gov/pubmed/19347029
http://dx.doi.org/10.1038/onc.2009.63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679420/
https://www.ncbi.nlm.nih.gov/pubmed/19347029
http://dx.doi.org/10.1038/onc.2009.63

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