Oxidative and Excitatory Mechanisms of Developmental Neurotoxicity: Transcriptional Profiles for Chlorpyrifos, Diazinon, Dieldrin, and Divalent Nickel in PC12 Cells

BACKGROUND: Oxidative stress and excitotoxicity underlie the developmental neurotoxicity of numerous chemicals. OBJECTIVES: We compared the effects of organophosphates (chlorpyrifos and diazinon), an organo-chlorine (dieldrin), and a metal [divalent nickel (Ni(2+))] to determine how these mechanisms...

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Detalles Bibliográficos
Autores principales: Slotkin, Theodore A., Seidler, Frederic J.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679603/
https://www.ncbi.nlm.nih.gov/pubmed/19440498
http://dx.doi.org/10.1289/ehp.0800251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679603/
https://www.ncbi.nlm.nih.gov/pubmed/19440498
http://dx.doi.org/10.1289/ehp.0800251

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