Haploinsufficiency of DNA Damage Response Genes and their Potential Influence in Human Genomic Disorders

Genomic disorders are a clinically diverse group of conditions caused by gain, loss or re-orientation of a genomic region containing dosage-sensitive genes. One class of genomic disorder is caused by hemizygous deletions resulting in haploinsufficiency of a single or, more usually, several genes. Fo...

Descripción completa

Detalles Bibliográficos
Autor principal: O’Driscoll, Mark
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679649/
https://www.ncbi.nlm.nih.gov/pubmed/19440510
http://dx.doi.org/10.2174/138920208784340795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679649/
https://www.ncbi.nlm.nih.gov/pubmed/19440510
http://dx.doi.org/10.2174/138920208784340795

Ejemplares similares