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Drosophila Lethal Giant Larvae Neoplastic Mutant as a Genetic Tool for Cancer Modeling

Drosophila lethal giant larvae (lgl) is a tumour suppressor gene whose function in establishing apical-basal cell polarity as well as in exerting proliferation control in epithelial tissues is conserved between flies and mammals. Individuals bearing lgl null mutations show a gradual loss of tissue a...

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Detalles Bibliográficos
Autores principales: Froldi, F, Ziosi, M, Tomba, G, Parisi, F, Garoia, F, Pession, A, Grifoni, D
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679652/
https://www.ncbi.nlm.nih.gov/pubmed/19440511
http://dx.doi.org/10.2174/138920208784340786