Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome

Protein synthesis is catalyzed in the peptidyl transferase center (PTC), located in the large (50S) subunit of the ribosome. No high-resolution structure of the intact ribosome has contained a complete active site including both A- and P-site tRNAs. Additionally, though structures of the 50S subunit...

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Detalles Bibliográficos
Autores principales: Voorhees, Rebecca M., Weixlbaumer, Albert, Loakes, David, Kelley, Ann C., Ramakrishnan, V.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679717/
https://www.ncbi.nlm.nih.gov/pubmed/19363482
http://dx.doi.org/10.1038/nsmb.1577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679717/
https://www.ncbi.nlm.nih.gov/pubmed/19363482
http://dx.doi.org/10.1038/nsmb.1577

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