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Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome
Protein synthesis is catalyzed in the peptidyl transferase center (PTC), located in the large (50S) subunit of the ribosome. No high-resolution structure of the intact ribosome has contained a complete active site including both A- and P-site tRNAs. Additionally, though structures of the 50S subunit...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679717/ https://www.ncbi.nlm.nih.gov/pubmed/19363482 http://dx.doi.org/10.1038/nsmb.1577 |