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Genotyping and inflated type I error rate in genome-wide association case/control studies
BACKGROUND: One common goal of a case/control genome wide association study (GWAS) is to find SNPs associated with a disease. Traditionally, the first step in such studies is to assign a genotype to each SNP in each subject, based on a statistic summarizing fluorescence measurements. When the distri...
Autores principales: | Sampson, Joshua N, Zhao, Hongyu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679732/ https://www.ncbi.nlm.nih.gov/pubmed/19236714 http://dx.doi.org/10.1186/1471-2105-10-68 |
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