Incorporation of membrane-bound, mammalian-derived immunomodulatory proteins into influenza whole virus vaccines boosts immunogenicity and protection against lethal challenge

BACKGROUND: Influenza epidemics continue to cause morbidity and mortality within the human population despite widespread vaccination efforts. This, along with the ominous threat of an avian influenza pandemic (H5N1), demonstrates the need for a much improved, more sophisticated influenza vaccine. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Herbert, Andrew S, Heffron, Lynn, Sundick, Roy, Roberts, Paul C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679740/
https://www.ncbi.nlm.nih.gov/pubmed/19393093
http://dx.doi.org/10.1186/1743-422X-6-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679740/
https://www.ncbi.nlm.nih.gov/pubmed/19393093
http://dx.doi.org/10.1186/1743-422X-6-42

Ejemplares similares