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Modelling mitochondrial site polymorphisms to infer the number of segregating units and mutation rate

We present a mathematical model of mitochondrial inheritance evolving under neutral evolution to interpret the heteroplasmies observed at some sites. A comparison of the levels of heteroplasmies transmitted from mother to her offspring allows us to estimate the number N(x) of inherited mitochondrial...

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Detalles Bibliográficos
Autores principales: Hendy, Michael D., Woodhams, Michael D., Dodd, Andrew
Formato: Texto
Lenguaje:English
Publicado: The Royal Society 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679937/
https://www.ncbi.nlm.nih.gov/pubmed/19324622
http://dx.doi.org/10.1098/rsbl.2009.0104