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Modelling mitochondrial site polymorphisms to infer the number of segregating units and mutation rate
We present a mathematical model of mitochondrial inheritance evolving under neutral evolution to interpret the heteroplasmies observed at some sites. A comparison of the levels of heteroplasmies transmitted from mother to her offspring allows us to estimate the number N(x) of inherited mitochondrial...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679937/ https://www.ncbi.nlm.nih.gov/pubmed/19324622 http://dx.doi.org/10.1098/rsbl.2009.0104 |