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Modelling mitochondrial site polymorphisms to infer the number of segregating units and mutation rate

We present a mathematical model of mitochondrial inheritance evolving under neutral evolution to interpret the heteroplasmies observed at some sites. A comparison of the levels of heteroplasmies transmitted from mother to her offspring allows us to estimate the number N(x) of inherited mitochondrial...

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Detalles Bibliográficos
Autores principales:	Hendy, Michael D., Woodhams, Michael D., Dodd, Andrew
Formato:	Texto
Lenguaje:	English
Publicado:	The Royal Society 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679937/ https://www.ncbi.nlm.nih.gov/pubmed/19324622 http://dx.doi.org/10.1098/rsbl.2009.0104

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