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IL-15 independent maintenance of virus-specific CD8(+) T cells in the CNS during chronic infection
The role of IL-15 in T cell survival was examined during chronic CNS coronavirus infection. Similar numbers of virus-specific CD8(+) T cells were retained in the CNS of IL-15(−/−) and wt mice, consistent with loss of IL-2/15 receptor (CD122) expression. IL-15 deficiency also had no affect on IL-7 re...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679951/ https://www.ncbi.nlm.nih.gov/pubmed/19106006 http://dx.doi.org/10.1016/j.jneuroim.2008.11.005 |