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Functional Profiling Reveals Critical Role for miRNA in Differentiation of Human Mesenchymal Stem Cells

BACKGROUND: Mesenchymal stem (MS) cells are excellent candidates for cell-based therapeutic strategies to regenerate injured tissue. Although human MS cells can be isolated from bone marrow and directed to differentiate by means of an osteogenic pathway, the regulation of cell-fate determination is...

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Detalles Bibliográficos
Autores principales: Schoolmeesters, Angela, Eklund, Teresa, Leake, Devin, Vermeulen, Annaleen, Smith, Queta, Force Aldred, Shelley, Fedorov, Yuriy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680014/
https://www.ncbi.nlm.nih.gov/pubmed/19440384
http://dx.doi.org/10.1371/journal.pone.0005605