Lipid Raft-Dependent FcεRI Ubiquitination Regulates Receptor Endocytosis through the Action of Ubiquitin Binding Adaptors

The best characterized role for ubiquitination of membrane receptors is to negatively regulate signaling by targeting receptors for lysosomal degradation. The high affinity receptor for IgE (FcεRI) expressed on mast cells and basophils is rapidly ubiquitinated upon antigen stimulation. However, the...

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Detalles Bibliográficos
Autores principales: Molfetta, Rosa, Gasparrini, Francesca, Peruzzi, Giovanna, Vian, Laura, Piccoli, Mario, Frati, Luigi, Santoni, Angela, Paolini, Rossella
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680016/
https://www.ncbi.nlm.nih.gov/pubmed/19440386
http://dx.doi.org/10.1371/journal.pone.0005604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680016/
https://www.ncbi.nlm.nih.gov/pubmed/19440386
http://dx.doi.org/10.1371/journal.pone.0005604

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