Deleted in Liver Cancer 1 (DLC1) Utilizes a Novel Binding Site for Tensin2 PTB Domain Interaction and Is Required for Tumor-Suppressive Function

BACKGROUND: Deleted in liver cancer 1 (DLC1) is a Rho GTPase-activating protein (RhoGAP) frequently deleted and underexpressed in hepatocellular carcinoma (HCC) as well as in other cancers. Recent independent studies have shown interaction of DLC1 with members of the tensin focal adhesion protein fa...

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Detalles Bibliográficos
Autores principales: Chan, Lo-Kong, Ko, Frankie Chi Fat, Ng, Irene Oi-Lin, Yam, Judy Wai Ping
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680019/
https://www.ncbi.nlm.nih.gov/pubmed/19440389
http://dx.doi.org/10.1371/journal.pone.0005572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680019/
https://www.ncbi.nlm.nih.gov/pubmed/19440389
http://dx.doi.org/10.1371/journal.pone.0005572

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