Cargando…

Myocardial Overexpression of Mecr, a Gene of Mitochondrial FAS II Leads to Cardiac Dysfunction in Mouse

It has been recently recognized that mammalian mitochondria contain most, if not all, of the components of fatty acid synthesis type II (FAS II). Among the components identified is 2-enoyl thioester reductase/mitochondrial enoyl-CoA reductase (Etr1/Mecr), which catalyzes the NADPH-dependent reductio...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Zhijun, Leskinen, Hanna, Liimatta, Erkki, Sormunen, Raija T., Miinalainen, Ilkka J., Hassinen, Ilmo E., Hiltunen, J. Kalervo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680037/
https://www.ncbi.nlm.nih.gov/pubmed/19440339
http://dx.doi.org/10.1371/journal.pone.0005589