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Myocardial Overexpression of Mecr, a Gene of Mitochondrial FAS II Leads to Cardiac Dysfunction in Mouse
It has been recently recognized that mammalian mitochondria contain most, if not all, of the components of fatty acid synthesis type II (FAS II). Among the components identified is 2-enoyl thioester reductase/mitochondrial enoyl-CoA reductase (Etr1/Mecr), which catalyzes the NADPH-dependent reductio...
Autores principales: | Chen, Zhijun, Leskinen, Hanna, Liimatta, Erkki, Sormunen, Raija T., Miinalainen, Ilkka J., Hassinen, Ilmo E., Hiltunen, J. Kalervo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680037/ https://www.ncbi.nlm.nih.gov/pubmed/19440339 http://dx.doi.org/10.1371/journal.pone.0005589 |
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