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Thiazole Antibiotics Target FoxM1 and Induce Apoptosis in Human Cancer Cells
Forkhead box M1 (FoxM1) oncogenic transcription factor represents an attractive therapeutic target in the fight against cancer, because it is overexpressed in a majority of human tumors. Recently, using a cell-based assay system we identified thiazole antibiotic Siomycin A as an inhibitor of FoxM1 t...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680058/ https://www.ncbi.nlm.nih.gov/pubmed/19440351 http://dx.doi.org/10.1371/journal.pone.0005592 |