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Hedging against Antiviral Resistance during the Next Influenza Pandemic Using Small Stockpiles of an Alternative Chemotherapy

BACKGROUND: The effectiveness of single-drug antiviral interventions to reduce morbidity and mortality during the next influenza pandemic will be substantially weakened if transmissible strains emerge which are resistant to the stockpiled antiviral drugs. We developed a mathematical model to test th...

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Detalles Bibliográficos
Autores principales: Wu, Joseph T., Leung, Gabriel M., Lipsitch, Marc, Cooper, Ben S., Riley, Steven
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680070/
https://www.ncbi.nlm.nih.gov/pubmed/19440354
http://dx.doi.org/10.1371/journal.pmed.1000085